Advanced Practice – Neutropenic Enterocolitis

Neutropenic Enterocolitis aka typhlitis, necrotizing enterocolitis, ileocecal syndrome

Definition:

  • intestinal mucosal wall edema and disruption of wall integrity in a neutropenic patient 

Pathogenesis:

  • Weakened immune system --> intestinal overgrowth --> invasion of opportunistic bacteria.
  • May lead to sepsis and bowel perforation.
  • Mortality  22%-50%.

Patient population:

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Advanced Practice – New Sepsis Guidelines Ignite Controversy!

The Surviving Sepsis Campaign has published a 2018 update to their guidelines for sepsis care. The new recommendations have sparked major controversy in the emergency medicine, critical care, and infectious disease communities. Read on for a brief summary of the most controversial points and links to further reading!

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Advanced Practice: New C-diff guidelines!

This week's post comes courtesy of our ED pharmacist Rachel Rafeq. Surprise! Metronidazole is no longer first line therapy for c-diff infections! Check out this handy table for the updated guidelines from the Infectious Disease Society of America for the latest treatment regimens

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