Advanced Practice – Neutropenic Enterocolitis

Neutropenic Enterocolitis aka typhlitis, necrotizing enterocolitis, ileocecal syndrome

Definition:

  • intestinal mucosal wall edema and disruption of wall integrity in a neutropenic patient 

Pathogenesis:

  • Weakened immune system --> intestinal overgrowth --> invasion of opportunistic bacteria.
  • May lead to sepsis and bowel perforation.
  • Mortality  22%-50%.

Patient population:

Category (Day):