Very nice mnemonic for Cavity lesion DDx in cxray: Cavity, C: Cancer or Mets, A: autoimmune; granulomas from, V: vascular (both bland and septic pulmonary embolus), I: infection(TB, fungall), T: trama (pneumatocoeles), Y: youth (congenital pulmonary airways malformation) Reference
We are very familiar with the term of Angioedema. Mostly comes from ACE-In but has a large ddx from NSAIDS to hereditary to idiopathic. There is an article in Academic EM that is discussing the treatment options for Angioedema. They categorize Angioedema to histaminergic-mediated vs Bradykini-meiated. In ED usually we do not know the underline disease of patient . we may find with history that patient has hereditary angioedema(HAE), but we can not diagnose the pathology in an acute setting specifically with a patient with airway concern. I recommend you to read this article in AEM.
Link to Abstract
I was giving lecture regarding this topic and some challenging concepts in SCC including IV therapy, oxygen therapy, blood transfusion, and always could not give a comprehensive reference to back myself up. This is a great article in Clinics of North America to support evidence based medicine on this topic.
Link to Pubmed
Morphine can affect functionality of Clopidogrel. There is an article in JACC, March 2014, that showed “Morphine delays clopidogrel absorption, decreases plasma levels of clopidogrel active metabolite, and retards and diminishes its effects, which can lead to treatment failure in susceptible individuals”. This will bring a problem with patient that the pain is not controlled with Nitro and now the choice of pain meds is….
Link to website
Alpha blocker (Tamsulosin , Flomax) originally is used for medical treatment of BPH. There are growing concerns that alpha blocker can be used in treatment of ureteral stone due to same affect on bladder and prostate, relaxation of muscle fiber. The recent Cochrane database review showed that compare with Nifedipine (ca channel blocker), alpha blocker has higher stone-free rate and a shorter time to stone expulsion. They recommended this medication to adjunct pain meds for patients with ureteral stone.
Link to article
Medical Principles and Practice published an article that uses a structured teaching tools to summarized 5 Hs and 5 Ts in PEA cardiac arrest, Lets start with 5 Hs(Hyper and Hypo K, Hypoxia, Hydrogen, Hypovolemia and Hypothermia) and 5 Ts( Tension PTX, Tamponade, Trauma, Toxins, Thrombosis), a very routine practice in ACLS guideline, But this method by Litmann L, et al, seems simplified that approach to a Narrow or Wide complex and I believe this will help us when we are doing CPR to approach better. If You see a Narrow complex PEA on the monitor you should think about mechanical right ventricle issues such as Tamponade. PE, Tension PTX, mechanical hyperinflation, and Acute MI, cardiac rupture. the answer should be Ultrasound and see hyperdynamic LV. The term of pseudo PEA refers to the mechanical causes are not directly related to abnormal myocardial performance. If there is a Wide complex PEA, we should think about Sever Hyper K, Sodium channel blocker Toxicity, and Acute MI,Pump Failure, use of US will let us to know about hypokinetic vs Akinetic cardiac activity. Based on this protocol treatment is easy in Narrow complex we will treat the cause, and based on Wide complex we will give IV calcium chloride and Nahco3.
Medical Principles and Practices