The TRANSFUSE trial has just been published in the New England Journal of Medicine – a huge congratulations to all the authors from the ANZICS Clinical Trials Group, including Jamie Cooper, Alistair Nicholl, and Dash Gantner from our Alfred ICU / INTENSIVE team.

This methodologically rigorous trial was a huge undertaking and involved about 5000 patients from 59 sites in 5 countries. It compared the effect of transfusing the freshest available red cells with that of standard-issue (oldest available) red cells high-risk critically ill patients… which has important implications for the supply and storage of blood for transfusion.

Read the article to see what it showed… or just skim through the Twitter responses if you’re lazy 😉

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CICM Second Part Exam Practice SAQs 13092017

As prepared by Chris Nickson, here are the practice written questions from a recent CICM Second Part exam practice session at The Alfred ICU, with recommended reading from’s Critical Care Compendium and other FOAM sources:


Discuss the issues concerning spontaneous breathing during mechanical ventilation in patients with acute respiratory distress syndrome (ARDS).

Learn more here:

Spontaneous breathing and mechanical ventilation


Outline the specific therapies used in the management of:

  1. phaeochromocytoma (25%)
  2. myxoedema coma (25%)
  3. hypercalcaemia (25%)
  4. carcinoid syndrome (25%)

Learn more here:

Carcinoid Syndrome


Myxoedema Coma



With respect to the Guillain Barre Syndrome (GBS):

  1. a) Outline how you distinguish between GBS and Critical Illness Polymyoneuropathy (CIP) (50%)
  2. b) What are the current treatment options in GBS? Briefly outline the supporting evidence (20%)
  3. c) What is the prognosis of GBS and what factors are associated with a worse outcome? (30%)


Learn more here:

CICM SAQ 2013.1 Q10

ICU Acquired Weakness (ICUAW)

Guillian-Barré Syndrome (GBS)


You can access all the previous practice questions since 2014 here:
See this link on INTENSIVE for exam resources:

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