Intubation during CPR was associated with worse survival and brain health

"Stop chest compressions for a minute while I intubate this patient!" That refrain must have been heard tens of thousands of times during CPR after cardiac arrest before 2010, when the American Heart Association's (AHA) Advanced Cardiac Life Support (ACLS) guidelines advised resuscitation teams not to interrupt chest compressions to place advanced airways, unless a patient [... read more]

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FDA approves betrixapan for extended DVT/PE prophylaxis

The US Food and Drug Administration (FDA) approved betrixaban (Bevyxxa), a new oral anticoagulant for prevention of venous thromboembolism (VTE) in hospitalized medical patients with risk factors for DVT/PE. With betrixaban, manufacturer Portola will seek to expand a tiny market niche it could immediately dominate: prophylaxis of DVT/PE extending for about a month after hospital [... read more]

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Is hypothermia harmful after in-hospital cardiac arrest?

Will "therapeutic" hypothermia someday need to be renamed? After a rush of optimism surrounding small trials showing large benefits from hypothermia to 33° after out-of-hospital cardiac arrest, hospitals and intensivists flocked to provide hypothermia to all victims of cardiac arrest (in- or out-of-hospital). When the much more powerful TTM trial showed no benefit of deep cooling [... read more]

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